Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29569443 | 0.82 | MAOA (0.41) | MAOAMAOBNISCHGAANPSR1 | |
| SCHEMBL2971412 | 0.82 | MAOA (0.41) | MAOAMAOBNISCHGAANPSR1 | |
| Hydrochloric Acid SCHEMBL19744197 | 0.81 | MAOA (0.39) | MAOAMAOBNISCHGAANPSR1 | |
| SCHEMBL990074 | 0.76 | MAOA (0.42) | MAOAMAOBGAANPSR1LMNA | |
| SCHEMBL30505283 | 0.76 | MAOA (0.42) | MAOAMAOBGAANPSR1LMNA | |
| Hydrochloric Acid SCHEMBL6994202 | 0.75 | MAOA (0.41) | MAOAMAOBGAANPSR1LMNA | |
| SCHEMBL3629324 | 0.75 | MAOB (0.37) | MAOAMAOBGAA | |
| Trifluoroacetic Acid SCHEMBL29570875 | 0.73 | MAOA (0.33) | MAOAMAOBGAAATM | |
| SCHEMBL13176581 | 0.72 | MAOA (0.38) | MAOAMAOBGAANPSR1ATM | |
| Acetic Acid SCHEMBL27738056 | 0.72 | MAOA (0.38) | MAOAMAOBGAANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395834-A | Antiarthritic agents or cardiovascular disorders | ADIR ET COMPAGNIE (FR) | 1995-03-07 | — | — | US | disclosed |
| US-5393775-A | Administering a (2-chromanyl)alkylcarboxylic acid for disorders connected with peroxidation processes | ADIR ET COMPAGNIE (FR) | 1995-02-28 | — | — | US | disclosed |
| US-4578380-A | 5H-[1]benzopyrano[2,3-d]pyrimidine derivatives useful for controlling lesions of the gastric and duodenal mucous membranes | WARNER-LAMBERT COMPANY (US) | 1986-03-25 | — | — | US | disclosed |