Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984287 | 0.75 | SHMT2 (0.47) | ITGB3ITGA2BF2SHMT2 | |
| SCHEMBL6980921 | 0.73 | ITGB3 (0.58) | ITGB3ITGA2B | |
| SCHEMBL9261117 | 0.71 | ITGB3 (0.45) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL9260617 | 0.71 | ITGB3 (0.45) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL12323108 | 0.70 | F10 (0.46) | ITGB3ITGA2BF2 | |
| SCHEMBL9257934 | 0.69 | ITGB3 (0.42) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL9425678 | 0.69 | ITGB3 (0.42) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL9260554 | 0.69 | ITGB3 (0.42) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL9426346 | 0.67 | F2 (0.43) | ITGB3ITGA2BF2 | |
| SCHEMBL3290955 | 0.67 | ITGB3 (0.81) | ITGB3ITGA2BF2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378727-A | ADMINISTERING TO MAMMALS | G. D. SEARLE & CO. (US) | 1995-01-03 | — | — | US | disclosed |
| EP-0630366-A1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. Searle & Co. (US) | 1994-12-28 | — | — | EP | disclosed |
| US-5254573-A | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| WO-1993008164-A1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-04-29 | — | — | WO | disclosed |
| EP-0539343-A1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |