Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262045 | 0.84 | MKNK1 (0.47) | ALDH1A1CYP1A2PTGS2NOTUMTDP1 | |
| SCHEMBL22143673 | 0.81 | MKNK1 (0.52) | ALDH1A1CYP1A2CYP2D6HPGDHIF1A | |
| SCHEMBL19214262 | 0.81 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP2D6HPGDHIF1A | |
| SCHEMBL27399076 | 0.77 | PTGS2 (0.51) | ALDH1A1CYP1A2CYP2D6HPGDHIF1A | |
| SCHEMBL22510633 | 0.76 | ALDH1A1 (0.63) | ALDH1A1CYP1A2CYP2D6HPGDHIF1A | |
| SCHEMBL24784278 | 0.74 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2D6HPGDHIF1A | |
| SCHEMBL29205308 | 0.74 | ALDH1A1 (0.57) | ALDH1A1CYP1A2CYP2D6HPGDHIF1A | |
| SCHEMBL22185265 | 0.71 | HSP90AA1 (0.42) | PTGS2NOTUMGRM1RAB9A | |
| SCHEMBL10022328 | 0.70 | ALDH1A1 (0.57) | ALDH1A1CYP1A2CYP2D6NOTUMTDP1 | |
| SCHEMBL25442241 | 0.70 | CYP3A4 (0.51) | CYP2D6PTGS2NOTUMTDP1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135997-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A LACTAM OR BENZENESULFONAMIDE COMPOUND | SHIONOGI & CO., LTD. (JP) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135997-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A LACTAM OR BENZENESULFONAMIDE COMPOUND | BACE1, STS, APP | ALDH1A1 3654/4885CYP1A2 1696/4885CYP2D6 464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.