Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.42 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | CPS1 | P31327 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256320 | 0.97 | MGLL (0.45) | MGLLSMN1; SMN2ALDH1A1LMNAUSP2 | |
| SCHEMBL9263304 | 0.88 | MGLL (0.47) | MGLLSMN1; SMN2ALDH1A1CACNA2D1CACNA1B | |
| SCHEMBL9257899 | 0.86 | ALDH1A1 (0.42) | MGLLALDH1A1LMNANPSR1CACNA2D1 | |
| SCHEMBL9261257 | 0.85 | ALDH1A1 (0.40) | MGLLALDH1A1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL9264047 | 0.85 | MGLL (0.44) | MGLLSMN1; SMN2ALDH1A1NPSR1CACNA2D1 | |
| SCHEMBL9254614 | 0.84 | MGLL (0.43) | MGLLALDH1A1LMNANPSR1CACNA2D1 | |
| SCHEMBL9254998 | 0.83 | ALDH1A1 (0.51) | MGLLALDH1A1NPSR1CACNA2D1CACNA1B | |
| SCHEMBL9257887 | 0.83 | MGLL (0.41) | MGLLALDH1A1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL9262507 | 0.82 | KMT2A (0.48) | MGLLALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL9262611 | 0.81 | ALDH1A1 (0.39) | MGLLALDH1A1NPSR1CACNA2D1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |