SCHEMBL9259535

SCHEMBL9259535

O=P(Oc1cccc(Cl)c1)(Oc1cccc(Cl)c1)Oc1cccc(Cl)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.59
CYP2D6 P10635 1/20 0.59
CYP2C9 P11712 1/20 0.59
CYP2C19 P33261 1/20 0.59
HTT P42858 2/20 0.50
WDR5 P61964 1/20 0.42
OGG1 O15527 1/20 0.41
MAPK1 P28482 2/20 0.41
LMNA P02545 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CYP3A4 P08684 2/20 0.40
TSHR P16473 2/20 0.40
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
RXRG P48443 1/20 0.40
ALDH1A1 P00352 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
KDM4E B2RXH2 1/20 0.39
SRC P12931 1/20 0.39
SLC6A4 P31645 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8849562 0.90 CYP1A2 (0.54) CYP1A2CYP2D6CYP2C9CYP2C19HTT
SCHEMBL31561763 0.85 CYP1A2 (0.57) CYP1A2CYP2D6CYP2C9CYP2C19HTT
SCHEMBL8849551 0.85 CYP1A2 (0.57) CYP1A2CYP2D6CYP2C9CYP2C19HTT
SCHEMBL11099147 0.85 CYP1A2 (0.57) CYP1A2CYP2D6CYP2C9CYP2C19HTT
SCHEMBL29093880 0.83 CYP1A2 (0.56) CYP1A2CYP2D6CYP2C9CYP2C19HTT
SCHEMBL7602618 0.83 SRC (0.58) CYP1A2CYP2D6CYP2C9CYP2C19HTT
SCHEMBL11053438 0.82 CYP1A2 (0.54) CYP1A2CYP2D6CYP2C9CYP2C19HTT
SCHEMBL27042296 0.79 KMT2A (0.50) CYP1A2CYP2D6CYP2C9CYP2C19CYP3A4
SCHEMBL78015 0.77 SRC (0.54) CYP1A2CYP2D6CYP2C9CYP2C19HTT
SCHEMBL25513746 0.77 SRC (0.54) CYP1A2CYP2D6CYP2C9CYP2C19HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5403503-A Containing a mixture of polyoxyalkylene glycol, polyester, phosphate and(or) phosphite IDEMITSU KOSAN CO., LTD. (JP) 1995-04-04 US claimed
US-9920083-B2 Image recording paper medium and image recording method FUJIFILM CORPORATION (JP) 2018-03-20 US disclosed
US-20160250866-A1 IMAGE RECORDING PAPER MEDIUM AND IMAGE RECORDING METHOD FUJIFILM CORPORATION (JP) 2016-09-01 US disclosed
EP-0135587-A4 DEFINED SEQUENCE SINGLE STRAND OLIGONUCLEOTIDES INCORPORATING REPORTER GROUPS, PROCESS FOR THE CHEMICAL SYNTHESIS THEREOF, AND NUCLEOSIDES USEFUL IN SUCH SYNTHESIS. MOLECULAR BIOSYSTEMS INC (US) 1986-04-02 EP disclosed
EP-0135587-A1 DEFINED SEQUENCE SINGLE STRAND OLIGONUCLEOTIDES INCORPORATING REPORTER GROUPS, PROCESS FOR THE CHEMICAL SYNTHESIS THEREOF, AND NUCLEOSIDES USEFUL IN SUCH SYNTHESIS. MOLECULAR BIOSYSTEMS INC (US) 1985-04-03 EP disclosed
WO-1984003285-A1 DEFINED SEQUENCE SINGLE STRAND OLIGONUCLEOTIDES INCORPORATING REPORTER GROUPS, PROCESS FOR THE CHEMICAL SYNTHESIS THEREOF, AND NUCLEOSIDES USEFUL IN SUCH SYNTHESIS MOLECULAR BIOSYSTEMS INC (US) 1984-08-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160250866-A1 IMAGE RECORDING PAPER MEDIUM AND IMAGE RECORDING METHOD PHOSPHO1, ITPR2, PPIP5K2 CYP1A2 3550/4885CYP2D6 4399/4885CYP2C9 3271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.