Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9010961 | 0.94 | DRD4 (0.60) | DRD4NPC1RAB9AS1PR1TSHR | |
| SCHEMBL9011270 | 0.90 | DRD4 (0.59) | DRD4NPC1RAB9ACYP1A2TSHR | |
| SCHEMBL9011016 | 0.87 | DRD4 (0.58) | DRD4NPC1RAB9ATSHRLMNA | |
| SCHEMBL7817809 | 0.86 | S1PR1 (0.53) | DRD4NPC1RAB9AS1PR1TSHR | |
| SCHEMBL27297526 | 0.84 | NPC1 (0.70) | DRD4NPC1RAB9ATSHRLMNA | |
| SCHEMBL9011045 | 0.83 | DRD4 (0.58) | DRD4NPC1RAB9ATSHRLMNA | |
| SCHEMBL9011162 | 0.83 | NPC1 (0.54) | DRD4NPC1RAB9ACYP1A2TSHR | |
| SCHEMBL7810022 | 0.83 | NPC1 (0.54) | DRD4NPC1RAB9AS1PR1TSHR | |
| SCHEMBL9011170 | 0.83 | LMNA (0.70) | DRD4NPC1CYP1A2TSHRLMNA | |
| SCHEMBL9011078 | 0.82 | CCR5 (0.54) | DRD4CYP1A2S1PR1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |