Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.32 |
| ▸ | GABRE | P78334 | 2/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.32 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615209 | 0.83 | CA1 (0.68) | CA1CA2TRPA1BBOX1BLM | |
| SCHEMBL292181 | 0.78 | — | — | |
| SCHEMBL234798 | 0.76 | CA1 (0.59) | CA1CA2TRPA1BLMGABRP | |
| SCHEMBL12077143 | 0.76 | CA1 (0.59) | CA1CA2TRPA1BBOX1BLM | |
| SCHEMBL15222311 | 0.74 | CA1 (0.56) | CA1CA2TRPA1BBOX1GABRP | |
| SCHEMBL104197 | 0.74 | CES2 (0.63) | CA1ALDH1A1TSHR | |
| SCHEMBL7846707 | 0.74 | CA1 (0.56) | CA1CA2TRPA1BBOX1BLM | |
| SCHEMBL108584 | 0.74 | CA1 (0.56) | CA1CA2TRPA1BBOX1BLM | |
| SCHEMBL104925 | 0.73 | CA1 (0.50) | CA1CA2TRPA1BLMCYP1A2 | |
| SCHEMBL7338051 | 0.73 | EGLN1 (0.37) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959312-A | Synthesis of antitumor alkaloid deoxyharringtonine and its precursor 3'-0-(5-methyl-2-oxohexanoyl)-cephalotaxine | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1976-05-25 | — | — | US | claimed |
| US-5476859-A | Inhibiting lentivirus by orally administering derivatives of 1,5-dideoxy-1,5-imino-D-glucitol | PARTIS RICHARD A (US) | 1995-12-19 | — | — | US | disclosed |
| US-5411970-A | Method of inhibiting lentivirus | G. D. SEARLE & CO. (US) | 1995-05-02 | — | — | US | disclosed |
| US-5310745-A | Acylated derivatives of 1,5-dideoxy-1,5-imino-D-glucitol, AIDS | G. D. SEARLE & CO. (US) | 1994-05-10 | — | — | US | disclosed |
| US-5221746-A | Inhibitors of visna virus; treatment of AIDS and ARC | G. D. SEARLE & CO. (US) | 1993-06-22 | — | — | US | disclosed |
| US-5144037-A | Viricides | G. D. SEARLE & CO. (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0494850-A2 | Novel antiviral compounds | G.D. Searle & Co. (US) | 1992-07-15 | — | — | EP | disclosed |
| US-3959312-A | Synthesis of antitumor alkaloid deoxyharringtonine and its precursor 3'-0-(5-methyl-2-oxohexanoyl)-cephalotaxine | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1976-05-25 | — | — | US | disclosed |