SCHEMBL9259701

SCHEMBL9259701

C=CCOc1ccccc1CC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
MAPT P10636 5/20 0.55
L3MBTL1 Q9Y468 4/20 0.55
NPSR1 Q6W5P4 1/20 0.55
KDM4E B2RXH2 4/20 0.53
LIG1 P18858 1/20 0.50
HPGD P15428 3/20 0.49
TSHR P16473 2/20 0.49
MAPK1 P28482 1/20 0.49
HSD17B10 Q99714 1/20 0.49
ATM Q13315 1/20 0.47
GAA P10253 1/20 0.47
SLC22A1 O15245 1/20 0.44
LMNA P02545 1/20 0.44
CYP1A2 P05177 1/20 0.44
ADRB2 P07550 1/20 0.44
ADRB1 P08588 1/20 0.44
HTR1A P08908 1/20 0.44
CYP2D6 P10635 1/20 0.44
HTR2A P28223 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9251894 0.85 ALDH1A1 (0.54) ALDH1A1MAPTL3MBTL1KDM4ELIG1
SCHEMBL2150775 0.84 ALDH1A1 (0.55) ALDH1A1MAPTL3MBTL1KDM4ELIG1
SCHEMBL2557802 0.82 L3MBTL1 (0.56) ALDH1A1MAPTL3MBTL1NPSR1KDM4E
SCHEMBL14151108 0.82 ALDH1A1 (0.54) ALDH1A1MAPTL3MBTL1KDM4ELIG1
SCHEMBL5085750 0.82 ALDH1A1 (0.54) ALDH1A1MAPTL3MBTL1KDM4EHPGD
Alcohol SCHEMBL27332773 0.82 ALDH1A1 (0.51) ALDH1A1MAPTL3MBTL1KDM4ELIG1
SCHEMBL3818208 0.81 KDM4E (0.50) ALDH1A1MAPTL3MBTL1KDM4ELIG1
1,2-Diallyloxybenzene SCHEMBL29768784 0.81 HPGD (0.60) ALDH1A1MAPTL3MBTL1KDM4ELIG1
1,2-Diallyloxybenzene SCHEMBL366516 0.81 HPGD (0.60) ALDH1A1MAPTL3MBTL1KDM4ELIG1
SCHEMBL1652184 0.81 ALDH1A1 (0.53) ALDH1A1MAPTL3MBTL1KDM4ELIG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101932325-A Ido inhibitors NEWLINK GENETICS 2010-12-29 CN claimed
US-5380654-A Process for the preparation of epoxides of means of microorganisms JAPAN ENERGY CORPORATION (JP) 1995-01-10 US claimed
US-5376539-A Aerobic incubation of allyl phenyl ether with arthrobacter, brevibacterium, corynebacterium, pseudomonas or rhodococcus yields glycidyl phenyl ether NIPPON MINING CO., LTD. (JP) 1994-12-27 US claimed
WO-2021183431-A1 FEM1B PROTEIN BINDING AGENTS AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-09-16 WO disclosed
US-9663649-B2 Stabilizers for polymers containing aliphatically-bound bromine DOW GLOBAL TECHNOLOGIES LLC (US) 2017-05-30 US disclosed
US-20170058118-A1 STABILIZERS FOR POLYMERS CONTAINING ALIPHATICALLY-BOUND BROMINE DCOMCO, INC. 2017-03-02 US disclosed
US-20160137826-A1 STABILIZERS FOR POLYMERS CONTAINING ALIPHATICALLY-BOUND BROMINE THE DOW CHEMICAL COMPANY 2016-05-19 US disclosed
US-8242183-B2 Brominated polymers as FR additives and polymer systems containing same DOW GLOBAL TECHNOLOGIES LLC (US) 2012-08-14 US disclosed
US-20110240906-A1 STABILIZERS FOR POLYMERS CONTAINING ALIPHATICALLY-BOUND BROMINE KRAM SHARI L 2011-10-06 US disclosed
US-20100317757-A1 Brominated Polymers as FR Additives and Polymer Systems Containing Same THE DOW CHEMICAL COMPANY 2010-12-16 US disclosed