Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 20/20 | 0.63 |
| ▸ | BCHE | P06276 | 16/20 | 0.63 |
| ▸ | GRIN1 | Q05586 | 14/20 | 0.63 |
| ▸ | GRIN2A | Q12879 | 14/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9257228 | 0.99 | ACHE (0.65) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL9255097 | 0.99 | ACHE (0.65) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL9248837 | 0.96 | ACHE (0.65) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL9252551 | 0.94 | ACHE (0.67) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL9248833 | 0.89 | ACHE (0.62) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL9248826 | 0.86 | MAPT (0.60) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL9255898 | 0.84 | ACHE (0.47) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL9257907 | 0.83 | ACHE (0.65) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL9257198 | 0.81 | ACHE (0.47) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL9261779 | 0.79 | ACHE (0.48) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391553-A | Increasing cholinergic functionin mammals | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-02-21 | — | — | US | claimed |
| US-5391553-A | Increasing cholinergic functionin mammals | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-02-21 | — | — | US | disclosed |
| EP-0282959-A2 | Substituted 9-amino-tetrahydro-acridines and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1988-09-21 | — | — | EP | disclosed |