Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 19/20 | 0.65 |
| ▸ | BCHE | P06276 | 10/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.65 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.62 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.57 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.57 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.57 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.57 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.57 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.57 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.57 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9248833 | 0.94 | ACHE (0.62) | ACHEBCHECHRM1EPHX2GRIN1 | |
| SCHEMBL9252551 | 0.89 | ACHE (0.67) | ACHEBCHECHRM1GRIN1GRIN2A | |
| SCHEMBL9248837 | 0.87 | ACHE (0.65) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL9255097 | 0.84 | ACHE (0.65) | ACHEBCHECHRM1GRIN1GRIN2A | |
| SCHEMBL9259735 | 0.83 | ACHE (0.63) | ACHEBCHEGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL9257228 | 0.82 | ACHE (0.65) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL9256012 | 0.81 | MAPT (0.54) | ACHEBCHECHRM1EPHX2GRIN1 | |
| SCHEMBL9255879 | 0.80 | ACHE (0.48) | ACHEBCHE | |
| SCHEMBL4271238 | 0.79 | ACHE (1.00) | ACHEBCHECHRM1EPHX2GRIN1 | |
| SCHEMBL12043409 | 0.78 | ACHE (1.00) | ACHEBCHECHRM1EPHX2GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391553-A | Increasing cholinergic functionin mammals | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-02-21 | — | — | US | claimed |
| US-5391553-A | Increasing cholinergic functionin mammals | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-02-21 | — | — | US | disclosed |