Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9264018 | 0.98 | HDAC1 (0.53) | HDAC1HDAC2HDAC4HDAC6HDAC3 | |
| SCHEMBL24784588 | 0.84 | HDAC1 (0.55) | HDAC1HDAC2HDAC4HDAC6HDAC3 | |
| SCHEMBL9509099 | 0.80 | HDAC1 (0.52) | HDAC1HDAC2HDAC4HDAC6HDAC3 | |
| SCHEMBL10184678 | 0.77 | HDAC1 (0.56) | HDAC1HDAC2HDAC4HDAC6HDAC3 | |
| SCHEMBL4278243 | 0.77 | ALOX15 (0.53) | HDAC1HDAC2HDAC4HDAC6HDAC3 | |
| SCHEMBL12827256 | 0.77 | CYP11B1 (0.55) | HDAC1HDAC2HDAC4HDAC6HDAC3 | |
| SCHEMBL5542313 | 0.77 | ALOX15 (0.53) | HDAC1HDAC2HDAC4HDAC6HDAC3 | |
| SCHEMBL9863750 | 0.77 | ALOX15 (0.53) | HDAC1HDAC2HDAC4HDAC6HDAC3 | |
| SCHEMBL4652514 | 0.77 | ALOX15 (0.53) | HDAC1HDAC2HDAC4HDAC6HDAC3 | |
| Hydrochloric Acid SCHEMBL9512459 | 0.75 | ALOX15 (0.52) | HDAC1HDAC2HDAC4HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5464849-A | N-hydroxyurea derivatives as antiallergy and antiinflammatory agents | PFIZER INC. (US) | 1995-11-07 | — | — | US | disclosed |