Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16888378 | 1.00 | ALDH1A1 (0.58) | ALDH1A1SIGMAR1DNM1TSHRCA12 | |
| SCHEMBL11587178 | 1.00 | — | — | |
| SCHEMBL28970288 | 1.00 | ALDH1A1 (0.58) | ALDH1A1SIGMAR1DNM1TSHRCA12 | |
| SCHEMBL9181110 | 1.00 | ALDH1A1 (0.58) | ALDH1A1SIGMAR1DNM1TSHRCA12 | |
| SCHEMBL14148257 | 0.97 | — | — | |
| SCHEMBL10197453 | 0.89 | — | — | |
| SCHEMBL29320413 | 0.87 | TSHR (0.48) | ALDH1A1SIGMAR1DNM1TSHREPHX1 | |
| SCHEMBL8497654 | 0.86 | ALDH1A1 (0.74) | ALDH1A1TSHREPHX1TDP1MEN1 | |
| SCHEMBL13294288 | 0.86 | ALDH1A1 (0.74) | ALDH1A1TSHREPHX1TDP1MEN1 | |
| SCHEMBL20702046 | 0.86 | ALDH1A1 (0.74) | ALDH1A1TSHREPHX1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656029-A1 | CROSSLINKED POLYMERIC AMMONIUM SALTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-06-07 | — | — | EP | disclosed |