Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021410 | 1.00 | HDAC3 (0.39) | HDAC3HDAC1PRMT5TP53HTT | |
| SCHEMBL9021457 | 0.85 | HDAC3 (0.40) | HDAC3HDAC1PRMT5TP53HTT | |
| SCHEMBL9021460 | 0.85 | HDAC3 (0.40) | HDAC3HDAC1PRMT5TP53HTT | |
| SCHEMBL9267454 | 0.84 | HDAC3 (0.42) | HDAC3HDAC1PRMT5LMNAALDH1A1 | |
| SCHEMBL9021316 | 0.84 | HDAC3 (0.42) | HDAC3HDAC1PRMT5LMNAALDH1A1 | |
| SCHEMBL9258956 | 0.81 | HDAC3 (0.40) | HDAC3HDAC1PRMT5HTTTSHR | |
| SCHEMBL9021885 | 0.81 | HDAC3 (0.40) | HDAC3HDAC1PRMT5HTTTSHR | |
| SCHEMBL6600262 | 0.81 | ALDH1A1 (0.44) | HDAC3HDAC1PRMT5TP53HTT | |
| SCHEMBL9262462 | 0.80 | TP53 (0.48) | TP53HTTALDH1A1KMT2AMRGPRX4 | |
| SCHEMBL9021287 | 0.80 | TP53 (0.48) | TP53HTTALDH1A1KMT2AMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5416068-A | Alpha-phenylacrylic acid derivatives, their preparation and their use for controlling pests and harmful fungi | BASF AKTIENGESELLSCHAFT (DE) | 1995-05-16 | — | — | US | disclosed |
| US-5298527-A | Insecticides | BASF AKTIENGESELLSCHAFT (DE) | 1994-03-29 | — | — | US | disclosed |