Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.38 |
| ▸ | NAMPT | P43490 | 9/20 | 0.37 |
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9261369 | 0.94 | SIGMAR1 (0.42) | SIGMAR1CHRNB2CHRNA4CYP11B2CYP11B1 | |
| SCHEMBL9252931 | 0.86 | TIPARP (0.37) | SIGMAR1NAMPTTIPARPMITFALDH1A1 | |
| SCHEMBL9252937 | 0.83 | TIPARP (0.37) | SIGMAR1NAMPTTIPARPMITFALDH1A1 | |
| SCHEMBL9255186 | 0.78 | CYP2A6 (0.44) | ALDH1A1LMNA | |
| SCHEMBL9259806 | 0.74 | IDH1 (0.43) | CYP11B2MITFALDH1A1LMNARAB9A | |
| SCHEMBL9252905 | 0.74 | IDH1 (0.40) | CYP11B2MITFALDH1A1LMNARAB9A | |
| SCHEMBL13019295 | 0.73 | SMN1; SMN2 (0.40) | SIGMAR1CYP11B2CYP11B1CYP19A1CYP17A1 | |
| SCHEMBL8136850 | 0.73 | SMN1; SMN2 (0.40) | SIGMAR1CYP11B2CYP11B1CYP19A1CYP17A1 | |
| SCHEMBL8271969 | 0.72 | SIGMAR1 (0.46) | SIGMAR1CHRNB2CHRNA4NAMPTMITF | |
| SCHEMBL828249 | 0.72 | XIAP (0.39) | TIPARPMITFALDH1A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135997-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A LACTAM OR BENZENESULFONAMIDE COMPOUND | SHIONOGI & CO., LTD. (JP) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135997-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A LACTAM OR BENZENESULFONAMIDE COMPOUND | BACE1, STS, APP | SIGMAR1 1154/4885CHRNB2 2171/4885CHRNA4 2231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.