Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 14/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9252937 | 0.94 | TIPARP (0.37) | TIPARPNAMPTSIGMAR1MITFALDH1A1 | |
| SCHEMBL9259830 | 0.86 | SIGMAR1 (0.42) | TIPARPNAMPTSIGMAR1MITFALDH1A1 | |
| SCHEMBL9261369 | 0.83 | SIGMAR1 (0.42) | TIPARPNAMPTSIGMAR1MITFALDH1A1 | |
| SCHEMBL5956084 | 0.78 | CYP1A2 (0.41) | — | |
| SCHEMBL9252905 | 0.75 | IDH1 (0.40) | MITFALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL9259806 | 0.75 | IDH1 (0.43) | MITFALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL828249 | 0.73 | XIAP (0.39) | TIPARPMITFALDH1A1LMNARAB9A | |
| SCHEMBL13000004 | 0.72 | BMPR1B (0.49) | SIGMAR1MITFALDH1A1LMNARAB9A | |
| SCHEMBL14560232 | 0.72 | BMPR1B (0.46) | SIGMAR1MITFALDH1A1LMNARAB9A | |
| SCHEMBL7878390 | 0.72 | MITF (0.43) | TIPARPNAMPTSIGMAR1MITFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135997-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A LACTAM OR BENZENESULFONAMIDE COMPOUND | SHIONOGI & CO., LTD. (JP) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135997-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A LACTAM OR BENZENESULFONAMIDE COMPOUND | BACE1, STS, APP | TIPARP 4754/4885NAMPT 1564/4885SIGMAR1 1154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.