Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15932107 | 0.91 | HPGD (0.46) | HPGDALDH1A1HSD17B10KDM4ECYP1A2 | |
| SCHEMBL20524093 | 0.90 | HPGD (0.45) | HPGDALDH1A1HSD17B10KDM4ECYP1A2 | |
| SCHEMBL892010 | 0.87 | CYP1A2 (0.46) | HPGDALDH1A1HSD17B10KDM4ECYP1A2 | |
| SCHEMBL15931414 | 0.87 | HPGD (0.58) | HPGDALDH1A1HSD17B10KDM4ECYP1A2 | |
| SCHEMBL346324 | 0.86 | HPGD (0.48) | HPGDALDH1A1HSD17B10KDM4ECYP1A2 | |
| SCHEMBL15931887 | 0.84 | HPGD (0.50) | HPGDALDH1A1HSD17B10KDM4ECYP1A2 | |
| SCHEMBL31644605 | 0.84 | HPGD (0.47) | HPGDALDH1A1HSD17B10KDM4ECYP1A2 | |
| SCHEMBL28069664 | 0.84 | SMN1; SMN2 (0.50) | HPGDALDH1A1HSD17B10KDM4ECYP1A2 | |
| SCHEMBL6371541 | 0.83 | MAPT (0.56) | HPGDALDH1A1HSD17B10KDM4ECYP1A2 | |
| SCHEMBL15932116 | 0.83 | CYP4F2 (0.47) | HPGDALDH1A1HSD17B10KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439932-A | Anticholesterol agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5306728-A | Substituted amine derivatives having antihyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0448078-A2 | Substituted amine derivatives having anti-hyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |