Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5243287 | 0.86 | MRGPRX4 (0.51) | SMN1; SMN2HSD17B10MAPK1MRGPRX4TP53 | |
| SCHEMBL9259869 | 0.84 | HPGD (0.47) | SMN1; SMN2HSD17B10MAPK1TP53MAPT | |
| SCHEMBL18255998 | 0.81 | MRGPRX4 (0.52) | SMN1; SMN2HSD17B10MAPK1MRGPRX4TP53 | |
| SCHEMBL18973243 | 0.81 | MRGPRX4 (0.52) | SMN1; SMN2HSD17B10MAPK1MRGPRX4TP53 | |
| SCHEMBL4551138 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2HSD17B10MAPK1MRGPRX4TP53 | |
| SCHEMBL9047880 | 0.79 | MRGPRX4 (0.58) | SMN1; SMN2HSD17B10MAPK1MRGPRX4TP53 | |
| SCHEMBL10644438 | 0.79 | MRGPRX4 (0.55) | SMN1; SMN2HSD17B10MAPK1MRGPRX4TP53 | |
| SCHEMBL8145313 | 0.79 | MRGPRX4 (0.51) | SMN1; SMN2HSD17B10MAPK1MRGPRX4TP53 | |
| SCHEMBL10641694 | 0.79 | MRGPRX4 (0.51) | SMN1; SMN2HSD17B10MAPK1MRGPRX4TP53 | |
| SCHEMBL10644274 | 0.79 | MRGPRX4 (0.58) | SMN1; SMN2HSD17B10MAPK1MRGPRX4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105566324-A | Hydroxyl purine compound and application thereof | GOOD DOCTOR PHARMACEUTICAL GROUP CO LTD | 2016-05-11 | — | — | CN | disclosed |