Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265506 | 0.97 | PREP (0.47) | PREPTDP1MAPTATMALDH1A1 | |
| SCHEMBL9519307 | 0.84 | PREP (0.42) | PREPTDP1MAPTATMALDH1A1 | |
| SCHEMBL9399827 | 0.84 | ALDH1A1 (0.45) | TDP1MAPTATMALDH1A1HPGD | |
| SCHEMBL9258915 | 0.83 | PREP (0.46) | PREPTDP1MAPTATMALDH1A1 | |
| SCHEMBL9399415 | 0.83 | ALDH1A1 (0.42) | TDP1MAPTATMALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL9399783 | 0.82 | ALDH1A1 (0.43) | TDP1MAPTATMALDH1A1HPGD | |
| SCHEMBL9020650 | 0.81 | TDP1 (0.44) | TDP1MAPTATMALDH1A1HPGD | |
| SCHEMBL9020800 | 0.81 | CCR5 (0.42) | TDP1MAPTATMALDH1A1HPGD | |
| SCHEMBL9519199 | 0.81 | PREP (0.43) | PREPTDP1MAPTATMALDH1A1 | |
| SCHEMBL9020217 | 0.81 | CCR5 (0.43) | TDP1MAPTATMALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420122-A | MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0272455-B1 | 3-Pyrrolidinylthio-1-azabicyclo [3.2.0] hept-2-ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-10 | — | — | EP | disclosed |
| US-5138064-A | Chemical intermediate for penicillin derivative | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| US-4921852-A | CARBAPENICILLINS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-05-01 | — | — | US | disclosed |
| EP-0272455-A1 | 3-Pyrrolidinylthio-1-azabicyclo [3.2.0] hept-2-ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-29 | — | — | EP | disclosed |