Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | RHOA | P61586 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259980 | 1.00 | ALDH1A1 (0.47) | ALDH1A1CYP3A4RECQLCYP4F2CYP4A11 | |
| SCHEMBL9281030 | 0.82 | ALDH1A1 (0.59) | ALDH1A1CYP3A4RECQLCYP4F2CYP4A11 | |
| SCHEMBL9272281 | 0.82 | ALDH1A1 (0.59) | ALDH1A1CYP3A4RECQLCYP4F2CYP4A11 | |
| SCHEMBL27825942 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CYP3A4RECQLCYP4F2CYP4A11 | |
| SCHEMBL10858214 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CYP3A4RECQLCYP4F2CYP4A11 | |
| SCHEMBL27480698 | 0.79 | NFE2L2 (0.50) | ALDH1A1TSHRKDM4EPKMHDAC4 | |
| SCHEMBL4683483 | 0.77 | PPARG (0.47) | ALDH1A1CYP3A4RECQLCYP4F2CYP4A11 | |
| SCHEMBL6599668 | 0.77 | CYP4F2 (0.50) | ALDH1A1CYP3A4RECQLCYP4F2CYP4A11 | |
| SCHEMBL6599676 | 0.77 | CYP4F2 (0.50) | ALDH1A1CYP3A4RECQLCYP4F2CYP4A11 | |
| SCHEMBL4683487 | 0.77 | PPARG (0.47) | ALDH1A1CYP3A4RECQLCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439932-A | Anticholesterol agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5306728-A | Substituted amine derivatives having antihyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0448078-A2 | Substituted amine derivatives having anti-hyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |