SCHEMBL9259982

SCHEMBL9259982

CCCCCOCCc1ccc(C(C)=O)cc1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.50
HSD17B10 Q99714 1/20 0.50
THRA P10827 6/20 0.49
THRB P10828 6/20 0.49
GAA P10253 1/20 0.49
RARB P10826 6/20 0.47
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.46
ALDH1A1 P00352 1/20 0.46
RARA P10276 1/20 0.46
MAPT P10636 1/20 0.46
MTOR P42345 1/20 0.46
SPHK1 Q9NYA1 1/20 0.45
PLK1 P53350 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9255950 0.98 GAA (0.51) L3MBTL1HSD17B10THRATHRBGAA
SCHEMBL10866320 0.95 L3MBTL1 (0.51) L3MBTL1HSD17B10THRATHRBGAA
SCHEMBL9256285 0.94 THRA (0.56) HSD17B10THRATHRBRARBKMT2A
SCHEMBL9251080 0.94 HSD17B10 (0.54) L3MBTL1HSD17B10THRATHRBGAA
SCHEMBL9252434 0.92 THRA (0.55) HSD17B10THRATHRBGAARARB
SCHEMBL9260102 0.90 HSD17B10 (0.50) L3MBTL1HSD17B10THRATHRBGAA
SCHEMBL9257866 0.90 L3MBTL1 (0.54) L3MBTL1HSD17B10THRATHRBGAA
SCHEMBL9256025 0.89 HSD17B10 (0.56) L3MBTL1HSD17B10THRATHRBGAA
SCHEMBL11612809 0.88 KMT2A (0.59) L3MBTL1HSD17B10GAAKMT2AALDH1A1
SCHEMBL9260821 0.87 RARB (0.64) RARBKMT2AMEN1ALDH1A1RARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5385693-A Having rapid response and low phase transition temperature SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-01-31 US disclosed
EP-0357372-B1 Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element SUMITOMO CHEMICAL CO (JP) 1994-11-17 EP disclosed
US-5264151-A Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-11-23 US disclosed
US-5124070-A High speed response SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-06-23 US disclosed
EP-0357372-A2 Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-03-07 EP disclosed