Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.44 |
| ▸ | PDE4A | P27815 | 5/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PPOX | P50336 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083691 | 0.84 | NPC1 (0.44) | SCN9ARAB9ANPC1PDE4DPDE4B | |
| SCHEMBL7931893 | 0.83 | SCN9A (0.52) | SCN9APDE4DPDE4BPDE4APDE4C | |
| SCHEMBL8083764 | 0.82 | SCN9A (0.54) | SCN9ARAB9ANPC1PDE4DPDE4B | |
| SCHEMBL9407126 | 0.82 | NPSR1 (0.51) | POLBRAB9ANPC1NPSR1MEN1 | |
| SCHEMBL7922423 | 0.80 | SCN9A (0.48) | SCN9ANPSR1PDE4DPDE4BPDE4A | |
| SCHEMBL8191955 | 0.77 | SCN9A (0.46) | SCN9ANPSR1PDE4DPDE4BPDE4A | |
| SCHEMBL28282010 | 0.77 | NPC1 (0.56) | POLBRAB9ANPC1NPSR1MEN1 | |
| SCHEMBL24960688 | 0.76 | NPC1 (0.52) | POLBRAB9ANPC1NPSR1MEN1 | |
| SCHEMBL5382561 | 0.76 | NPC1 (0.52) | POLBRAB9ANPC1NPSR1MEN1 | |
| SCHEMBL8763572 | 0.76 | NPSR1 (0.51) | SCN9ANPSR1PDE4DPDE4BPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391807-A | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5344953-A | Fluorobenzene derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-09-06 | — | — | US | disclosed |
| US-5281742-A | Bis(fluorophenyl) carbonate derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-01-25 | — | — | US | disclosed |
| EP-0496347-A2 | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-07-29 | — | — | EP | disclosed |