Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCUN1D1 | Q96GG9 | 8/20 | 0.62 |
| ▸ | UBE2M | P61081 | 7/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257297 | 0.89 | DCUN1D1 (0.56) | DCUN1D1UBE2MKDM4ECYP1A2CYP3A4 | |
| SCHEMBL9256017 | 0.88 | ALDH1A1 (0.66) | DCUN1D1UBE2MALDH1A1TP53 | |
| SCHEMBL9263254 | 0.87 | ALDH1A1 (0.53) | DCUN1D1UBE2MPOLBALDH1A1TP53 | |
| SCHEMBL10587275 | 0.86 | DCUN1D1 (0.61) | DCUN1D1UBE2MPOLBRAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9260026 | 0.86 | ALDH1A1 (0.52) | DCUN1D1UBE2MPOLBALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL9256917 | 0.85 | DCUN1D1 (0.60) | DCUN1D1UBE2MPOLBRAB9AALDH1A1 | |
| SCHEMBL9256258 | 0.85 | TP53 (0.67) | DCUN1D1UBE2MPOLBNPC1RAB9A | |
| SCHEMBL13911285 | 0.84 | DCUN1D1 (0.55) | DCUN1D1UBE2MKDM4ECYP1A2CYP3A4 | |
| SCHEMBL9255607 | 0.84 | ALDH1A1 (0.53) | DCUN1D1UBE2MPOLBNPC1RAB9A | |
| SCHEMBL9261691 | 0.84 | ALDH1A1 (0.53) | DCUN1D1UBE2MPOLBALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5384425-A | Diurea derivatives useful as medicaments and processes for the preparation thereof | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1995-01-24 | — | — | US | disclosed |
| EP-0325397-B1 | DIUREA DERIVATIVES USEFUL AS MEDICAMENTS AND PROCESSES FOR THE PREPARATION THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |
| US-5166429-A | Enzyme inhibitors of acylcoenzyme A cholesterol transferase as anticholesterol agents or antideposit agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |
| US-5091419-A | Anticholesterol agent | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-02-25 | — | — | US | disclosed |