Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | MC3R | P41968 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.34 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL355917 | 0.60 | ALDH1A1 (0.40) | ADORA2ALMNAHPGDBLMALDH1A1 | |
| SCHEMBL20203174 | 0.60 | ADORA2A (0.48) | ADORA2AADORA2BGDAPIK3CDPOLB | |
| SCHEMBL18794726 | 0.60 | LMNA (0.42) | ADORA2AADORA2BGDAPIK3CDPOLB | |
| SCHEMBL4435082 | 0.59 | ADORA2A (0.35) | ADORA2AADORA2BGDAPIK3CDPOLB | |
| SCHEMBL14438644 | 0.58 | ADORA2A (0.48) | ADORA2AADORA2BGDAPIK3CDPOLB | |
| SCHEMBL18794727 | 0.58 | CYP3A4 (0.40) | ADORA2AADORA2BGDAPIK3CDPOLB | |
| SCHEMBL14088794 | 0.57 | LMNA (0.40) | ADORA2AADORA2BGDAPIK3CDPOLB | |
| SCHEMBL15519349 | 0.57 | ADORA2A (0.41) | ADORA2AADORA2BGDAPIK3CDPOLB | |
| SCHEMBL10328045 | 0.57 | ADORA2A (0.37) | ADORA2AADORA2BGDAPIK3CDPOLB | |
| SCHEMBL23234870 | 0.56 | CDK1 (0.38) | ADORA2AADORA2BGDAPIK3CDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995031459-A1 | MORPHOLINO-SUBUNIT COMBINATORIAL LIBRARY AND METHOD | ANTIVIRALS INC. (US) | 1995-11-23 | — | — | WO | disclosed |