Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255813 | 0.94 | MEN1 (0.52) | MEN1KMT2ATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL9266990 | 0.91 | ALDH1A1 (0.50) | MEN1KMT2ATSHRALDH1A1LMNA | |
| SCHEMBL9262713 | 0.89 | GAA (0.54) | MEN1KMT2ATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL9260856 | 0.88 | TSHR (0.50) | MEN1KMT2ATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL9261538 | 0.88 | ALDH1A1 (0.50) | MEN1KMT2ATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL9260852 | 0.88 | TSHR (0.50) | MEN1KMT2ATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL9261137 | 0.86 | MEN1 (0.58) | MEN1KMT2ATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL9259923 | 0.86 | CNR1 (0.44) | MEN1KMT2ATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL9259912 | 0.83 | TBXA2R (0.54) | MEN1KMT2ATSHRALDH1A1TBXA2R | |
| SCHEMBL9253452 | 0.83 | TBXA2R (0.54) | MEN1KMT2ATSHRALDH1A1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407951-A | Anticoagulants, muscle relaxants, bronchodilators | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-18 | — | — | US | disclosed |
| US-5140038-A | Thromboxane A2 antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-18 | — | — | US | disclosed |