Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9266990 | 0.88 | ALDH1A1 (0.50) | POLBALDH1A1LMNATSHRMEN1 | |
| SCHEMBL9260495 | 0.86 | MEN1 (0.53) | ALDH1A1SMN1; SMN2LMNATSHRMEN1 | |
| SCHEMBL9262713 | 0.86 | GAA (0.54) | POLBALDH1A1SMN1; SMN2TSHRTP53 | |
| SCHEMBL9255813 | 0.81 | MEN1 (0.52) | ALDH1A1SMN1; SMN2LMNATSHRMEN1 | |
| SCHEMBL4709273 | 0.81 | ALDH1A1 (0.58) | CYP19A1ALDH1A1SMN1; SMN2LMNALSS | |
| SCHEMBL20743530 | 0.78 | ALDH1A1 (0.60) | CYP19A1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL9259702 | 0.77 | ALDH1A1 (0.51) | ALDH1A1LMNATSHRMEN1KMT2A | |
| SCHEMBL17731245 | 0.76 | DGAT1 (0.46) | — | |
| SCHEMBL9260856 | 0.74 | TSHR (0.50) | POLBALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL9261538 | 0.74 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2LMNATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407951-A | Anticoagulants, muscle relaxants, bronchodilators | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-18 | — | — | US | disclosed |
| US-5140038-A | Thromboxane A2 antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-18 | — | — | US | disclosed |