Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYLK | Q15746 | 5/20 | 0.76 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.62 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.47 |
| ▸ | DLK1 | P80370 | 1/20 | 0.47 |
| ▸ | MAP3K10 | Q02779 | 1/20 | 0.47 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | TEK | Q02763 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | PRKCB | P05771 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCH | P24723 | 1/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265479 | 0.96 | MYLK (0.71) | MYLKROCK2PDGFRBMAP3K9DLK1 | |
| SCHEMBL9254743 | 0.88 | MYLK (0.69) | MYLKROCK2MAP3K9MAP3K10MAP3K11 | |
| SCHEMBL9544892 | 0.87 | MYLK (0.75) | MYLKROCK2MAP3K9DLK1MAP3K10 | |
| SCHEMBL9826964 | 0.87 | MYLK (0.59) | MYLKROCK2PDGFRBMAP3K9DLK1 | |
| SCHEMBL9544881 | 0.87 | MYLK (1.00) | MYLKROCK2MAP3K9DLK1MAP3K10 | |
| SCHEMBL9544714 | 0.83 | MYLK (0.93) | MYLKROCK2MAP3K9DLK1MAP3K10 | |
| SCHEMBL9263673 | 0.82 | ROCK2 (0.87) | MYLKROCK2PDGFRBMAP3K9MAP3K11 | |
| SCHEMBL9195167 | 0.80 | ROCK2 (0.74) | MYLKROCK2MAP3K9MAP3K11PRKD3 | |
| SCHEMBL9260091 | 0.77 | ROCK2 (0.78) | MYLKROCK2PDGFRBMAP3K9MAP3K11 | |
| SCHEMBL9263506 | 0.77 | ROCK2 (0.78) | MYLKROCK2PDGFRBMAP3K9MAP3K11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993024490-A1 | USE OF INDOLOCARBAZOLS IN AIDS TREATMENT | Gödecke Aktiengesellschaft (DE) | 1993-12-09 | — | — | WO | claimed |
| US-5438050-A | Indolocarbazole derivatives, processes for their preparation and compositions containing them | GODECKE AKTIENGESELLSCHAFT (DE) | 1995-08-01 | — | — | US | disclosed |
| WO-1993024490-A1 | USE OF INDOLOCARBAZOLS IN AIDS TREATMENT | Gödecke Aktiengesellschaft (DE) | 1993-12-09 | — | — | WO | disclosed |
| EP-0370236-B1 | INDOLOCARBAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1991-12-27 | — | — | EP | disclosed |
| EP-0370236-A1 | Indolocarbazole derivatives, processes for their preparation and their use as medicaments | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1990-05-30 | — | — | EP | disclosed |