Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | TACR2 | P21452 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
| ▸ | OGFRL1 | Q5TC84 | 3/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.33 |
| ▸ | PDE6D | O43924 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9267727 | 0.92 | HRH1 (0.39) | HRH1TACR2TACR1KDM4EPOLB | |
| SCHEMBL9263400 | 0.81 | STS (0.44) | KDM4EOPRM1OPRD1OGFRL1SMN1; SMN2 | |
| SCHEMBL9268872 | 0.80 | TACR2 (0.44) | HRH1TACR2TACR1KDM4EMEN1 | |
| SCHEMBL9258711 | 0.79 | REN (0.40) | HRH1TACR2TACR1KDM4EPOLB | |
| SCHEMBL9260703 | 0.77 | HRH1 (0.42) | HRH1TACR2TACR1KDM4EHSD17B10 | |
| SCHEMBL9258366 | 0.77 | HRH1 (0.63) | HRH1TACR2TACR1ALDH1A1 | |
| SCHEMBL9261042 | 0.77 | TACR2 (0.66) | HRH1TACR2TACR1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL9259556 | 0.76 | TACR2 (0.65) | HRH1TACR2TACR1KDM4EPOLB | |
| SCHEMBL9259439 | 0.75 | STS (0.44) | KDM4EKMT2AOPRM1OPRD1OGFRL1 | |
| SCHEMBL9268748 | 0.73 | HRH1 (0.41) | HRH1TACR2TACR1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380731-A | Antiallergic compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-01-10 | — | — | US | claimed |
| US-5380731-A | Antiallergic compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0561973-A1 | ANTIALLERGIC COMPOUNDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-09-29 | — | — | EP | disclosed |
| WO-1992010491-A1 | ANTIALLERGIC COMPOUNDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-25 | — | — | WO | disclosed |