Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 2/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257841 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1HPGDMEN1NPC1 | |
| SCHEMBL4581554 | 0.83 | KDM4E (0.40) | KDM4EALDH1A1HPGDMEN1NPC1 | |
| SCHEMBL3160917 | 0.79 | KDM4E (0.39) | KDM4EALDH1A1HPGDMEN1NPC1 | |
| SCHEMBL5097862 | 0.77 | KDM4E (0.40) | KDM4EALDH1A1HPGDMEN1NPC1 | |
| SCHEMBL3166406 | 0.76 | KDM4E (0.39) | KDM4EALDH1A1HPGDMEN1NPC1 | |
| SCHEMBL7821439 | 0.76 | NPC1 (0.37) | KDM4EALDH1A1HPGDMEN1NPC1 | |
| SCHEMBL3162160 | 0.76 | KDM4E (0.38) | KDM4EALDH1A1HPGDMEN1NPC1 | |
| SCHEMBL2599683 | 0.75 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGDMEN1NPC1 | |
| SCHEMBL2599681 | 0.75 | KDM4E (0.38) | KDM4EALDH1A1HPGDMEN1NPC1 | |
| SCHEMBL2400659 | 0.75 | KDM4E (0.38) | KDM4EALDH1A1HPGDMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5429774-A | FOR USE IN PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL, INC. (US) | 1995-07-04 | — | — | US | claimed |
| US-5429774-A | FOR USE IN PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL, INC. (US) | 1995-07-04 | — | — | US | disclosed |