Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30284405 | 0.84 | KDM4E (0.50) | KDM4EALDH1A1HPGDMEN1NPC1 | |
| SCHEMBL361847 | 0.84 | KDM4E (0.50) | KDM4EALDH1A1HPGDMEN1NPC1 | |
| SCHEMBL9260925 | 0.84 | KDM4E (0.38) | KDM4EALDH1A1HPGDMEN1NPC1 | |
| SCHEMBL8921625 | 0.81 | KDM4E (0.43) | KDM4EALDH1A1HPGDMEN1NPC1 | |
| SCHEMBL9104399 | 0.81 | KDM4E (0.40) | KDM4EALDH1A1HPGDMEN1NPC1 | |
| SCHEMBL9056690 | 0.80 | KDM4E (0.44) | KDM4EALDH1A1HPGDMEN1NPC1 | |
| SCHEMBL2517095 | 0.78 | KDM4E (0.45) | KDM4EALDH1A1HPGDMEN1NPC1 | |
| SCHEMBL1387642 | 0.75 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDMEN1NPC1 | |
| SCHEMBL9258580 | 0.75 | MEN1 (0.40) | KDM4EALDH1A1HPGDMEN1NPC1 | |
| SCHEMBL5615321 | 0.74 | SMN1; SMN2 (0.43) | KDM4EALDH1A1HPGDMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5429774-A | FOR USE IN PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL, INC. (US) | 1995-07-04 | — | — | US | claimed |
| US-5429774-A | FOR USE IN PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL, INC. (US) | 1995-07-04 | — | — | US | disclosed |