Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9264601 | 0.96 | LMNA (0.45) | LMNAGPR84FFAR1MAPTHMGCR | |
| SCHEMBL9425828 | 0.96 | LMNA (0.48) | LMNAGPR84FFAR1MAPTHMGCR | |
| SCHEMBL9261315 | 0.94 | LMNA (0.41) | LMNAGPR84FFAR1MAPTHMGCR | |
| SCHEMBL9266176 | 0.92 | LMNA (0.45) | LMNAGPR84FFAR1MAPTHMGCR | |
| SCHEMBL5057383 | 0.91 | LMNA (0.48) | LMNAGPR84FFAR1MAPTHMGCR | |
| SCHEMBL459538 | 0.91 | LMNA (0.48) | LMNAGPR84FFAR1MAPTHMGCR | |
| SCHEMBL1191304 | 0.91 | LMNA (0.48) | LMNAGPR84FFAR1MAPTHMGCR | |
| SCHEMBL17392527 | 0.91 | LMNA (0.48) | LMNAGPR84FFAR1MAPTHMGCR | |
| SCHEMBL11180648 | 0.91 | ALDH1A1 (0.36) | LMNA | |
| SCHEMBL23327979 | 0.87 | LMNA (0.48) | LMNAGPR84FFAR1MAPTHMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352689-A | Rhizoxin derivatives and their use as anti-tumor agents | SANKYO COMPANY, LIMITED (JP) | 1994-10-04 | — | — | US | claimed |
| US-5391564-A | E.g., rhizoxin-13-yl 3-methylthiopropionate; anticarcinogenic agents | SANKYO COMPANY, LIMITED (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5352689-A | Rhizoxin derivatives and their use as anti-tumor agents | SANKYO COMPANY, LIMITED (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0350315-B1 | RHIZOXIN DERIVATES AND THEIR USE AS ANTI-TUMOR AGENTS | SANKYO COMPANY LIMITED (JP) | 1993-06-16 | — | — | EP | disclosed |
| EP-0350315-A1 | Rhizoxin derivates and their use as anti-tumor agents | SANKYO COMPANY LIMITED (JP) | 1990-01-10 | — | — | EP | disclosed |