SCHEMBL9263127

SCHEMBL9263127

O=P(O)(O)CC(O)C(O)CO

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GABBR2 O75899 1/20 0.39
GABBR1 Q9UBS5 1/20 0.39
LMNA P02545 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TDP1 Q9NUW8 1/20 0.36
FOLH1 Q04609 6/20 0.34
KDM4E B2RXH2 1/20 0.33
MMP2 P08253 1/20 0.33
THRB P10828 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
NAALAD2 Q9Y3Q0 1/20 0.32
PDE4A P27815 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28589992 0.84 LMNA (0.48) GABBR2GABBR1LMNAL3MBTL1TDP1
E968 SCHEMBL31315354 0.82 LMNA (0.47) LMNAL3MBTL1TDP1KDM4EMMP2
E968 SCHEMBL20559013 0.82 LMNA (0.47) LMNAL3MBTL1TDP1KDM4EMMP2
E968 SCHEMBL29038531 0.79 LMNA (0.44) LMNAL3MBTL1TDP1KDM4EMMP2
E968 SCHEMBL5481653 0.77 LMNA (0.42) GABBR2GABBR1LMNAL3MBTL1TDP1
E968 SCHEMBL25298465 0.74 LMNA (0.61) LMNAL3MBTL1TDP1KDM4ETHRB
E968 SCHEMBL27767182 0.74
SCHEMBL88028 0.74 LMNA (0.40) LMNAL3MBTL1TDP1KDM4EMMP2
SCHEMBL20471 0.74
SCHEMBL6892726 0.74 LMNA (0.40) LMNAL3MBTL1TDP1KDM4EMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2992334-B1 NOVEL PHOSPHATIDYLALKANOLS AND COMPOSITIONS THEREOF Pethmark AB (SE) 2018-06-27 EP claimed
EP-2992334-B1 NOVEL PHOSPHATIDYLALKANOLS AND COMPOSITIONS THEREOF Pethmark AB (SE) 2018-06-27 EP disclosed
US-9784701-B2 Phosphatidylalkanols and compositions thereof Pethmark AB (SE) 2017-10-10 US disclosed
US-20170052132-A1 NOVEL PHOSPHATIDYLALKANOLS AND COMPOSITIONS THEREOF Pethmark AB (SE) 2017-02-23 US disclosed
US-9499572-B2 Phosphatidylalkanols and compositions thereof Pethmark AB (SE) 2016-11-22 US disclosed
EP-2992334-A1 NOVEL PHOSPHATIDYLALKANOLS AND COMPOSITIONS THEREOF PEthmark AB (SE) 2016-03-09 EP disclosed
US-20160052946-A1 NOVEL PHOSPHATIDYLALKANOLS AND COMPOSITIONS THEREOF Pethmark AB (SE) 2016-02-25 US disclosed
WO-2014178787-A1 NOVEL PHOSPHATIDYLALKANOLS AND COMPOSITIONS THEREOF Pethmark AB (SE) 2014-11-06 WO disclosed
US-5384406-A Hydrolysis resistant; agriculture chemical anions ISP INVESTMENTS INC. (US) 1995-01-24 US disclosed
US-5221791-A Hydrolysis resistant ISP INVESTMENTS INC. (US) 1993-06-22 US disclosed
WO-1992021656-A1 WATER-SOLUBLE BIOLOGICALLY ACTIVE AMMONIUM SALTS ISP INVESTMENTS INC. (US) 1992-12-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160052946-A1 NOVEL PHOSPHATIDYLALKANOLS AND COMPOSITIONS THEREOF PHOSPHO1, SGMS1, DEGS1 GABBR2 3777/4885GABBR1 4198/4885LMNA 1521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.