Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 5/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.59 |
| ▸ | BCR | P11274 | 5/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP4B1 | P13584 | 2/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.47 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.47 |
| ▸ | CYP2A7 | P20853 | 2/20 | 0.47 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.47 |
| ▸ | CYP2F1 | P24903 | 2/20 | 0.47 |
| ▸ | CYP2C18 | P33260 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12203517 | 0.86 | ALDH1A1 (0.49) | ABL1ABCB1BCRCYP1A1CYP1A2 | |
| SCHEMBL28972370 | 0.84 | ABL1 (0.58) | ABL1ABCB1BCRCYP1A1CYP1A2 | |
| SCHEMBL12203379 | 0.83 | ABL1 (0.56) | ABL1ABCB1BCRCA1CA2 | |
| SCHEMBL31090715 | 0.77 | ABL1 (0.50) | ABL1ABCB1BCRCYP1A1CYP1A2 | |
| SCHEMBL28582164 | 0.76 | TRPA1 (0.43) | ABL1ABCB1BCRCYP1A2CYP3A4 | |
| SCHEMBL9261481 | 0.75 | ATM (0.47) | TRPA1TP53TSHRALDH1A1KMT2A | |
| SCHEMBL23746850 | 0.75 | TRPA1 (0.45) | CA1CA2TRPA1TSHRALDH1A1 | |
| SCHEMBL9254216 | 0.74 | CYP1A1 (0.53) | CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8 | |
| SCHEMBL29833702 | 0.73 | ALDH1A1 (0.46) | CYP2A6CYP2B6CA2TRPA1TSHR | |
| SCHEMBL291792 | 0.73 | ALDH1A1 (0.46) | CYP2A6CYP2B6CA2TRPA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135997-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A LACTAM OR BENZENESULFONAMIDE COMPOUND | SHIONOGI & CO., LTD. (JP) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135997-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A LACTAM OR BENZENESULFONAMIDE COMPOUND | BACE1, STS, APP | ABL1 2940/4885ABCB1 121/4885BCR 306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.