Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.60 |
| ▸ | RORC | P51449 | 12/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11553625 | 0.89 | NR4A2 (0.69) | NR4A2RORCCYP2C9KDM4ECYP1A2 | |
| SCHEMBL31601057 | 0.89 | NR4A2 (0.69) | NR4A2RORCCYP2C9KDM4ECYP1A2 | |
| SCHEMBL2610312 | 0.84 | KDM4E (0.71) | NR4A2RORCCYP2C9KDM4ECYP1A2 | |
| SCHEMBL12918558 | 0.84 | NR4A2 (0.63) | NR4A2RORCCYP2C9KDM4ECYP1A2 | |
| SCHEMBL27697431 | 0.84 | NR4A2 (0.56) | NR4A2RORCCYP2C9KDM4ECYP1A2 | |
| SCHEMBL25281959 | 0.82 | RORC (0.55) | NR4A2RORCCYP2C9KDM4ECYP1A2 | |
| SCHEMBL15421267 | 0.81 | NR4A2 (0.56) | NR4A2RORCCYP2C9KDM4ECYP1A2 | |
| SCHEMBL9266995 | 0.81 | NR4A2 (0.52) | NR4A2RORCCYP2C9KDM4ECYP1A2 | |
| SCHEMBL27933789 | 0.81 | RORC (0.53) | NR4A2RORCCYP2C9KDM4ECYP1A2 | |
| SCHEMBL17176538 | 0.79 | NR4A2 (0.69) | NR4A2RORCCYP2C9KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150555-B2 | Amide derivative and use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-10-06 | — | — | US | disclosed |
| US-9150555-B2 | Amide derivative and use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-10-06 | — | — | US | disclosed |
| EP-2657230-A1 | AMIDE DERIVATIVE AND USE THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2013-10-30 | — | — | EP | disclosed |
| US-20130211075-A1 | AMIDE DERIVATIVE AND USE THEREOF | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-08-15 | — | — | US | disclosed |
| US-20130211075-A1 | AMIDE DERIVATIVE AND USE THEREOF | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-08-15 | — | — | US | disclosed |
| US-5466704-A | N-substituted imidazole and benzimidazole derivatives useful as angiotenson II antagonists | E. R. SQUIBB & SONS, INC. (US) | 1995-11-14 | — | — | US | disclosed |
| EP-0501269-A1 | Imidazole and benzimidazole derivatives | E.R. SQUIBB & SONS, INC. (US) | 1992-09-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130211075-A1 | AMIDE DERIVATIVE AND USE THEREOF | IL2, IL4, IL5 | NR4A2 2022/4885RORC 118/4885CYP2C9 1551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.