Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 10/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9263151 | 1.00 | TBXAS1 (0.49) | TBXAS1SMN1; SMN2ALDH1A1KMT2ALMNA | |
| SCHEMBL9266639 | 0.88 | TBXAS1 (0.46) | TBXAS1SMN1; SMN2ALDH1A1KMT2ALMNA | |
| SCHEMBL9266643 | 0.88 | TBXAS1 (0.46) | TBXAS1SMN1; SMN2ALDH1A1KMT2ALMNA | |
| SCHEMBL9268521 | 0.85 | TBXAS1 (0.69) | TBXAS1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL10567974 | 0.81 | QPCT (0.50) | TBXAS1SMN1; SMN2ALDH1A1KMT2ALMNA | |
| SCHEMBL9260322 | 0.81 | MEN1 (0.56) | TBXAS1ALDH1A1KMT2ALMNAATM | |
| SCHEMBL10567981 | 0.81 | QPCT (0.50) | TBXAS1SMN1; SMN2ALDH1A1KMT2ALMNA | |
| SCHEMBL9260327 | 0.81 | MEN1 (0.56) | TBXAS1ALDH1A1KMT2ALMNAATM | |
| SCHEMBL9263044 | 0.75 | TBXAS1 (0.52) | TBXAS1ALDH1A1 | |
| SCHEMBL8538923 | 0.75 | KDM4E (0.67) | SMN1; SMN2KMT2ALMNAATMCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274867-A2 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1988-07-20 | — | — | EP | claimed |
| US-5459144-A | Enterovirus and rhinovirus antiviral, antiinflammatory and antagonist of platelet activating factor | SCHERING CORPORATION (US) | 1995-10-17 | — | — | US | disclosed |
| US-5272167-A | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1993-12-21 | — | — | US | disclosed |
| EP-0560407-A1 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1993-09-15 | — | — | EP | disclosed |
| WO-1991000858-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS | SCHERING CORPORATION (US) | 1991-01-24 | — | — | WO | disclosed |
| EP-0407217-A1 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1991-01-09 | — | — | EP | disclosed |
| US-4851423-A | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1989-07-25 | — | — | US | disclosed |
| EP-0274867-A2 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1988-07-20 | — | — | EP | disclosed |