Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 6/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.42 |
| ▸ | QPCT | Q16769 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9266639 | 1.00 | TBXAS1 (0.46) | TBXAS1CYP19A1SMN1; SMN2TBXA2RQPCT | |
| SCHEMBL9263151 | 0.88 | TBXAS1 (0.49) | TBXAS1SMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL9263145 | 0.88 | TBXAS1 (0.49) | TBXAS1SMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL9268521 | 0.82 | TBXAS1 (0.69) | TBXAS1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2434454 | 0.75 | DRD4 (0.49) | SMN1; SMN2MEN1MAPK1KMT2A | |
| SCHEMBL2434453 | 0.75 | DRD4 (0.49) | SMN1; SMN2MEN1MAPK1KMT2A | |
| SCHEMBL7977340 | 0.75 | DRD4 (0.49) | SMN1; SMN2MEN1MAPK1KMT2A | |
| SCHEMBL8538923 | 0.75 | KDM4E (0.67) | SMN1; SMN2QPCTTSHRMEN1LMNA | |
| SCHEMBL9260327 | 0.74 | MEN1 (0.56) | TBXAS1CYP19A1QPCTALDH1A1MAPT | |
| SCHEMBL9260322 | 0.74 | MEN1 (0.56) | TBXAS1CYP19A1QPCTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274867-A2 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1988-07-20 | — | — | EP | claimed |
| US-5459144-A | Enterovirus and rhinovirus antiviral, antiinflammatory and antagonist of platelet activating factor | SCHERING CORPORATION (US) | 1995-10-17 | — | — | US | disclosed |
| US-5272167-A | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1993-12-21 | — | — | US | disclosed |
| EP-0560407-A1 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1993-09-15 | — | — | EP | disclosed |
| WO-1991000858-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS | SCHERING CORPORATION (US) | 1991-01-24 | — | — | WO | disclosed |
| EP-0407217-A1 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1991-01-09 | — | — | EP | disclosed |
| US-4851423-A | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1989-07-25 | — | — | US | disclosed |
| EP-0274867-A2 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1988-07-20 | — | — | EP | disclosed |