Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HSPA9 | P38646 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 4/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11691096 | 0.94 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPK1LMNAHTTTSHR | |
| SCHEMBL29895266 | 0.94 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPK1LMNAHTTTSHR | |
| SCHEMBL28449071 | 0.91 | ALDH1A1 (0.46) | SMN1; SMN2MAPK1LMNAHTTTSHR | |
| SCHEMBL28517552 | 0.85 | ALDH1A1 (0.46) | SMN1; SMN2MAPK1LMNAHTTTSHR | |
| SCHEMBL10652160 | 0.83 | ALDH1A1 (0.45) | SMN1; SMN2MAPK1LMNAHTTALDH1A1 | |
| SCHEMBL23795255 | 0.80 | MDM2 (0.43) | SMN1; SMN2MAPK1LMNAHTTTSHR | |
| SCHEMBL23795274 | 0.77 | MDM2 (0.43) | SMN1; SMN2MAPK1LMNAHTTTSHR | |
| SCHEMBL9356391 | 0.76 | LTA4H (0.46) | SMN1; SMN2LMNATSHRALDH1A1RAB9A | |
| SCHEMBL448167 | 0.76 | TSHR (0.47) | LMNATSHRALDH1A1TDP1CYP3A4 | |
| SCHEMBL21925718 | 0.73 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPK1LMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114436848-A | Synthesis method of 5(6) -amino-1- (4-aminophenyl) -1,3,3-trimethylindane | 山东华夏神舟新材料有限公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-111484412-A | Method for synthesizing compound containing indan structure | 上海华谊树脂有限公司 | 2020-08-04 | — | — | CN | disclosed |
| EP-0519368-B1 | Process for the purification of diaminodiphenyl compounds | BROMINE COMPOUNDS LTD (IL) | 1995-10-11 | — | — | EP | disclosed |
| US-5340445-A | Vacuum distillation in presence of at least one alkaline metal , sublimation inhibition | BROMINE COMPOUNDS LTD. (IL) | 1994-08-23 | — | — | US | disclosed |
| EP-0519368-A2 | Process for the purification of diaminodiphenyl compounds | Bromine Compounds Ltd. (IL) | 1992-12-23 | — | — | EP | disclosed |