Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19136708 | 0.73 | ALDH1A1 (0.41) | ALDH1A1PTK2BMAPTMEN1KMT2A | |
| SCHEMBL20262414 | 0.73 | CYP1A2 (0.44) | ALDH1A1MAPTMEN1KMT2ATSHR | |
| SCHEMBL11073868 | 0.72 | SRD5A1 (0.42) | ALDH1A1PTK2BMAPTMEN1KMT2A | |
| SCHEMBL11073873 | 0.72 | SRD5A1 (0.42) | ALDH1A1PTK2BMAPTMEN1KMT2A | |
| Bicarbonate SCHEMBL8601125 | 0.69 | CYP1A2 (0.55) | ALDH1A1TSHRCYP1A2ALOX15SRD5A2 | |
| SCHEMBL6622150 | 0.69 | SMN1; SMN2 (0.50) | ALDH1A1MAPTMEN1KMT2ATSHR | |
| SCHEMBL648276 | 0.68 | HPGD (0.42) | ALDH1A1MAPTMEN1KMT2ATSHR | |
| SCHEMBL19136697 | 0.68 | ALDH1A1 (0.37) | ALDH1A1PTK2BMAPTMEN1KMT2A | |
| SCHEMBL19136696 | 0.68 | ALDH1A1 (0.37) | ALDH1A1PTK2BMAPTMEN1KMT2A | |
| SCHEMBL989510 | 0.67 | KMT2A (0.70) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5436343-A | Thromboxane A2 receptor antagonist, thromoboxane A2 synthase inhibitor | ADIR ET COMPAGNIE (FR) | 1995-07-25 | — | — | US | disclosed |