SCHEMBL648276

SCHEMBL648276

N#CC(C(=O)O)=C1c2ccccc2-c2ccccc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2C9 P11712 2/20 0.42
CYP2C19 P33261 2/20 0.42
CYP3A4 P08684 1/20 0.42
ALDH1A1 P00352 6/20 0.40
IDO1 P14902 1/20 0.40
MAPT P10636 5/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 2/20 0.37
S100A4 P26447 1/20 0.36
TDP2 O95551 1/20 0.36
NSD2 O96028 1/20 0.36
PLA2G1B P04054 1/20 0.36
HSP90AA1 P07900 1/20 0.36
CCR6 P51684 1/20 0.36
ATG4B Q9Y4P1 1/20 0.36
MAPK1 P28482 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20243906 0.85 ELANE (0.42) HPGDCYP1A2CYP2C9CYP2C19CYP3A4
SCHEMBL15470875 0.82 ALDH1A1 (0.56) HPGDCYP1A2CYP2C9CYP2C19CYP3A4
SCHEMBL469110 0.82 SLC16A3 (0.43) HPGDCYP1A2CYP2C9CYP2C19CYP3A4
SCHEMBL20243905 0.78 ALDH1A1 (0.34) HPGDCYP1A2CYP2C9CYP2C19CYP3A4
SCHEMBL19136708 0.76 ALDH1A1 (0.41) HPGDCYP1A2CYP2C9CYP2C19CYP3A4
SCHEMBL19136690 0.76 ALDH1A1 (0.33) HPGDCYP1A2CYP2C9CYP2C19CYP3A4
SCHEMBL19136692 0.76 ALDH1A1 (0.33) HPGDCYP1A2CYP2C9CYP2C19CYP3A4
SCHEMBL15470890 0.74 ALDH1A1 (0.51) HPGDALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL15473384 0.73 IDO1 (0.46) HPGDCYP1A2CYP2C9CYP2C19CYP3A4
SCHEMBL9359866 0.73 CES1 (0.36) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120121524-A1 PHOTO-STABLE COSMETIC OR DERMATOLOGICAL COMPOSITIONS MUELLER STEFAN (DE) 2012-05-17 US claimed
US-20100143272-A1 Photo-stable cosmetic or dermatological compositions CIBA SPECIALTY CHEMICALS CORPORATION 2010-06-10 US claimed
EP-1793798-A1 PHOTO-STABLE COSMETIC OR DERMATOLOGICAL COMPOSITIONS Ciba Specialty Chemicals Holding Inc. (CH) 2007-06-13 EP claimed
WO-2006034968-A1 PHOTO-STABLE COSMETIC OR DERMATOLOGICAL COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-04-06 WO claimed
EP-1793798-B1 PHOTO-STABLE COSMETIC OR DERMATOLOGICAL COMPOSITIONS BASF SE (DE) 2016-04-20 EP disclosed
US-20120121524-A1 PHOTO-STABLE COSMETIC OR DERMATOLOGICAL COMPOSITIONS MUELLER STEFAN (DE) 2012-05-17 US disclosed
US-8119107-B2 Photo-stable cosmetic or dermatological compositions BASF SE (DE) 2012-02-21 US disclosed
EP-2194958-A2 SUNLESS TANNING COMPOSITION WITH PHOTOSTABILIZED SUNSCREEN PLAYTEX PRODUCTS, INC. (US) 2010-06-16 EP disclosed
US-20100143272-A1 Photo-stable cosmetic or dermatological compositions CIBA SPECIALTY CHEMICALS CORPORATION 2010-06-10 US disclosed
US-7648697-B2 Compounds derived from polyanhydride resins with film-forming, UV-absorbing, and photostabilizing properties, compositions containing same, and methods of using the same HALLSTAR INNOVATIONS CORP. (US) 2010-01-19 US disclosed
US-7648697-B2 Compounds derived from polyanhydride resins with film-forming, UV-absorbing, and photostabilizing properties, compositions containing same, and methods of using the same HALLSTAR INNOVATIONS CORP. (US) 2010-01-19 US disclosed
US-7648697-B2 Compounds derived from polyanhydride resins with film-forming, UV-absorbing, and photostabilizing properties, compositions containing same, and methods of using the same HALLSTAR INNOVATIONS CORP. (US) 2010-01-19 US disclosed
US-6800274-B2 UNSATURATED ESTERS INCLUDING DIPHENYLMETHYLENE AND/OR 9H-FLUORENE MOIETIES THE C.P. HALL COMPANY 2004-10-05 US disclosed
US-20040062726-A1 Novel photostabilizers, UV absorbers, and methods of photostabilizing a sunscreen composition BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2004-04-01 US disclosed
US-20040062726-A1 Novel photostabilizers, UV absorbers, and methods of photostabilizing a sunscreen composition BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2004-04-01 US disclosed
WO-2004026197-A2 NOVEL PHOTOSTABILIZERS, UV ABSORBERS, AND METHODS OF PHOTOSTABILIZING A SUNSCREEN COMPOSITION CPH INNOVATIONS CORPORATION (US) 2004-04-01 WO disclosed
US-20040057916-A1 Novel photostabilizers, UV absorbers, and methods of photostablizing a sunscreen composition THE C.P. HALL COMPANY 2004-03-25 US disclosed
US-20040057914-A1 Novel photostabilizers, UV absorbers, and methods of photostabilizing a sunscreen composition BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2004-03-25 US disclosed
US-20040057912-A1 Novel photostabilizers, UV absorbers, and methods of photostabilizing a sunscreen composition BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2004-03-25 US disclosed
US-20040057912-A1 Novel photostabilizers, UV absorbers, and methods of photostabilizing a sunscreen composition BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2004-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120121524-A1 PHOTO-STABLE COSMETIC OR DERMATOLOGICAL COMPOSITIONS NISCH, CUTA, MITF HPGD 422/4885CYP1A2 1874/4885CYP2C9 2596/4885
US-20040057912-A1 Novel photostabilizers, UV absorbers, and methods of photostabilizing a sunscreen composition UROD, ALAD, HMBS HPGD 100/4885CYP1A2 226/4885CYP2C9 51/4885
US-20040057916-A1 Novel photostabilizers, UV absorbers, and methods of photostablizing a sunscreen composition UROD, UNG, ALAD HPGD 441/4885CYP1A2 235/4885CYP2C9 148/4885
US-20040057914-A1 Novel photostabilizers, UV absorbers, and methods of photostabilizing a sunscreen composition UROD, UNG, HMBS HPGD 175/4885CYP1A2 199/4885CYP2C9 80/4885
US-20100143272-A1 Photo-stable cosmetic or dermatological compositions DBF4, CUTA, ARSA HPGD 1981/4885CYP1A2 1443/4885CYP2C9 3013/4885
US-20040062726-A1 Novel photostabilizers, UV absorbers, and methods of photostabilizing a sunscreen composition UROD, ALAD, UNG HPGD 161/4885CYP1A2 258/4885CYP2C9 50/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.