Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | UBE2N | P61088 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954842 | 0.83 | KMT2A (0.59) | SMN1; SMN2RAB9AKMT2APKMNPSR1 | |
| SCHEMBL24590651 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2RAB9AKMT2ANPSR1HPGD | |
| SCHEMBL3185330 | 0.79 | HPGD (0.78) | SMN1; SMN2RAB9AKMT2APKMNPSR1 | |
| SCHEMBL31552456 | 0.79 | SMN1; SMN2 (0.71) | SMN1; SMN2KMT2AHPGDHSD17B10ALDH1A1 | |
| SCHEMBL9267938 | 0.78 | HCRTR2 (0.65) | SMN1; SMN2KMT2APKMHPGDMEN1 | |
| SCHEMBL9270069 | 0.77 | POLB (0.50) | SMN1; SMN2KMT2ANPSR1HPGDHSD17B10 | |
| SCHEMBL9275347 | 0.77 | SMN1; SMN2 (0.72) | SMN1; SMN2RAB9AKMT2ANPSR1HPGD | |
| SCHEMBL29957873 | 0.77 | ALDH1A1 (0.72) | SMN1; SMN2RAB9AKMT2APKMNPSR1 | |
| SCHEMBL5462136 | 0.77 | HPGD (0.61) | SMN1; SMN2RAB9AKMT2APKMHPGD | |
| SCHEMBL2719871 | 0.77 | KMT2A (0.67) | SMN1; SMN2RAB9AKMT2APKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995029155-A1 | NOVEL ANTITUMOUR COMPOUNDS WITH ANTIMITOTIC ACTIVITY | PHARMACIA AB (SE) | 1995-11-02 | — | — | WO | disclosed |