Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | NPY1R | P25929 | 1/20 | 0.56 |
| ▸ | NPY2R | P49146 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6635632 | 0.87 | SMN1; SMN2 (0.66) | SMN1; SMN2RAB9AKMT2AHPGDNPY1R | |
| SCHEMBL24590651 | 0.84 | SMN1; SMN2 (1.00) | SMN1; SMN2RAB9AKMT2AHPGDNPSR1 | |
| SCHEMBL29956005 | 0.81 | SMN1; SMN2 (0.66) | SMN1; SMN2RAB9AKMT2AHPGDMAPT | |
| SCHEMBL4576519 | 0.81 | L3MBTL1 (0.63) | SMN1; SMN2HPGDALDH1A1LMNA | |
| SCHEMBL22209067 | 0.80 | HTT (0.60) | SMN1; SMN2HPGDHTTLMNA | |
| SCHEMBL9271748 | 0.79 | KMT2A (0.82) | SMN1; SMN2KMT2AHPGDNPSR1ALDH1A1 | |
| SCHEMBL8714203 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2HPGDHTTLMNA | |
| SCHEMBL5272168 | 0.78 | KMT2A (1.00) | SMN1; SMN2RAB9AKMT2AHPGDNPSR1 | |
| SCHEMBL9263271 | 0.77 | SMN1; SMN2 (0.68) | SMN1; SMN2RAB9AKMT2AHPGDNPSR1 | |
| SCHEMBL9871210 | 0.74 | RAB9A (0.69) | SMN1; SMN2RAB9AKMT2AHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995029155-A1 | NOVEL ANTITUMOUR COMPOUNDS WITH ANTIMITOTIC ACTIVITY | PHARMACIA AB (SE) | 1995-11-02 | — | — | WO | disclosed |