Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 11/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300300 | 1.00 | FKBP1A (0.48) | FKBP1AHTR2CNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4674934 | 0.91 | HTR2C (0.52) | FKBP1AHTR2CNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5873673 | 0.88 | FKBP1A (0.45) | FKBP1AHTR2CSMN1; SMN2 | |
| SCHEMBL15287785 | 0.87 | FKBP1A (0.46) | FKBP1A | |
| SCHEMBL9259424 | 0.85 | KLK7 (0.48) | FKBP1AHTR2C | |
| SCHEMBL29072821 | 0.84 | HTR2C (0.50) | FKBP1AHTR2CNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27736628 | 0.84 | HTR2C (0.51) | FKBP1AHTR2CTSHR | |
| SCHEMBL27757498 | 0.84 | HTR2C (0.51) | FKBP1AHTR2CTSHR | |
| SCHEMBL10589809 | 0.83 | SLC6A2 (0.52) | FKBP1AHTR2CNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8948803 | 0.83 | CYP2C19 (0.48) | FKBP1AHTR2CNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659190-A1 | ANTINEOPLASTIC HETERONAPHTHOQUINONES | BIOCHEM PHARMA INC (CA) | 1995-06-28 | — | — | EP | disclosed |
| WO-1994011382-A1 | ANTINEOPLASTIC HETERONAPHTHOQUINONES | BIOCHEM PHARMA INC. (CA) | 1994-05-26 | — | — | WO | disclosed |