Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 1/20 | 0.54 |
| ▸ | TUBB | P07437 | 1/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.54 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.54 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.54 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.54 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.54 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.54 |
| ▸ | CFTR | P13569 | 2/20 | 0.46 |
| ▸ | SDHB | P21912 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3878179 | 0.85 | TUBB4A (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4195184 | 0.83 | LMNA (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10667889 | 0.83 | TUBB4A (0.54) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28944494 | 0.83 | KDM4E (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29827383 | 0.83 | KDM4E (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL124080 | 0.82 | TUBB4A (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL30480593 | 0.82 | TUBB4A (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4476468 | 0.82 | TUBB4A (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL125591 | 0.82 | TUBB4A (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2435522 | 0.82 | TUBB4A (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835726-B | Compound for inhibiting tumor cell stem property and application thereof | 上海诺精生物科技有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-114835726-A | Compound for inhibiting dryness of tumor cells and application thereof | 上海诺精生物科技有限公司 | 2022-08-02 | — | — | CN | disclosed |
| US-8293900-B2 | Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators | MERCK SHARP & DOHME CORP (US) | 2012-10-23 | — | — | US | disclosed |
| US-8293900-B2 | Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators | MERCK SHARP & DOHME CORP (US) | 2012-10-23 | — | — | US | disclosed |
| US-20090170863-A1 | Acylated Spiropiperidine Derivatives as Melanocortin-4 Receptor Modulators | MERCK & CO., INC. (US) | 2009-07-02 | — | — | US | disclosed |
| US-20090170863-A1 | Acylated Spiropiperidine Derivatives as Melanocortin-4 Receptor Modulators | MERCK & CO., INC. (US) | 2009-07-02 | — | — | US | disclosed |
| WO-2007041052-A2 | ACYLATED SPIROPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2007-04-12 | — | — | WO | disclosed |
| US-5440043-A | To prepare chemcial intermediates for sulfonylurea herbicides; reacting enones with acetonitrile derivatives under basic conditions, cyclizing under acidic conditions | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-08-08 | — | — | US | disclosed |
| US-5332823-A | Herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-07-26 | — | — | US | disclosed |
| US-5235060-A | CERTAIN THREE COMPONENT IONIC SUBSTITUTED PYRIDINE COMPOUNDS AS INTERMEDIATES FOR PREPARATION AS HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-08-10 | — | — | US | disclosed |
| EP-0526732-A2 | Processes for the preparation of heterocyclic thiocarbamates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-02-10 | — | — | EP | disclosed |
| EP-0522392-A1 | Substituted pyridines and a process for their preparation | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-01-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170863-A1 | Acylated Spiropiperidine Derivatives as Melanocortin-4 Receptor Modulators | MC4R, MC5R, MC3R | TUBB4A 2291/4885TUBB 4054/4885TUBA3C 3620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.