Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9272694 | 0.79 | VHL (0.40) | — | |
| SCHEMBL17909916 | 0.78 | RORC (0.49) | L3MBTL1 | |
| SCHEMBL15374934 | 0.73 | SCN9A (0.53) | POLB | |
| SCHEMBL2872955 | 0.72 | KMT2A (0.51) | HTTRECQL | |
| SCHEMBL29374301 | 0.71 | BIRC5 (0.59) | L3MBTL1 | |
| SCHEMBL7213172 | 0.71 | BIRC5 (0.59) | L3MBTL1 | |
| SCHEMBL28779645 | 0.70 | MCL1 (0.51) | XDHPOLB | |
| SCHEMBL12670819 | 0.69 | RORC (0.58) | — | |
| SCHEMBL12670685 | 0.68 | — | — | |
| SCHEMBL6845146 | 0.68 | RXRA (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466704-A | N-substituted imidazole and benzimidazole derivatives useful as angiotenson II antagonists | E. R. SQUIBB & SONS, INC. (US) | 1995-11-14 | — | — | US | disclosed |