Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.51 |
| ▸ | PPARA | Q07869 | 8/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 4/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747337 | 0.87 | FFAR1 (0.53) | PPARGPPARAFFAR1SMPD1PPARD | |
| SCHEMBL4746718 | 0.85 | FFAR1 (0.50) | PPARGPPARAFFAR1SMPD1PPARD | |
| SCHEMBL9093694 | 0.85 | FFAR1 (0.67) | PPARGPPARAFFAR1 | |
| SCHEMBL9261947 | 0.80 | PPARG (0.49) | PPARGPPARAFFAR1PPARDERBB2 | |
| SCHEMBL9089772 | 0.79 | PPARG (0.53) | PPARGPPARAFFAR1SMPD1PPARD | |
| SCHEMBL9261466 | 0.79 | PPARG (0.47) | PPARGPPARAFFAR1PPARDERBB2 | |
| SCHEMBL9261471 | 0.79 | PPARG (0.47) | PPARGPPARAFFAR1PPARDERBB2 | |
| SCHEMBL9266531 | 0.79 | TP53 (0.51) | PPARGPPARASMPD1PPARD | |
| SCHEMBL4744035 | 0.77 | PPARA (0.65) | PPARGPPARAFFAR1 | |
| SCHEMBL4748565 | 0.76 | PPARG (0.60) | PPARGPPARAFFAR1SMPD1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459154-A | Enzyme inhibitors as antiinflammatory agents and treatment of atherosclerosis | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-10-17 | — | — | US | disclosed |