Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.65 |
| ▸ | PPARG | P37231 | 9/20 | 0.65 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748241 | 0.89 | PPARA (0.62) | PPARAPPARGFFAR1CYP2C9KCNH2 | |
| SCHEMBL4747337 | 0.86 | FFAR1 (0.53) | PPARAPPARGFFAR1 | |
| SCHEMBL4747894 | 0.86 | PPARA (0.62) | PPARAPPARGKDRGPBAR1CYSLTR1 | |
| SCHEMBL4746564 | 0.85 | PPARA (0.64) | PPARAPPARGKDRGPBAR1CYSLTR1 | |
| SCHEMBL4788097 | 0.82 | PPARA (0.56) | PPARAPPARGFFAR1 | |
| SCHEMBL4743964 | 0.78 | PPARA (0.57) | PPARAPPARG | |
| SCHEMBL4743974 | 0.78 | PPARA (0.57) | PPARAPPARG | |
| SCHEMBL4744522 | 0.77 | PPARA (0.56) | PPARAPPARG | |
| SCHEMBL4746718 | 0.77 | FFAR1 (0.50) | PPARAPPARGFFAR1 | |
| SCHEMBL5512060 | 0.77 | MAOB (0.63) | MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |