Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 18/20 | 0.43 |
| ▸ | CA4 | P22748 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA6 | P23280 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262639 | 0.91 | CA2 (0.44) | CA2CA4CA1CA12CA6 | |
| SCHEMBL9263188 | 0.90 | CA2 (0.45) | CA2CA4CA1CA12CA6 | |
| SCHEMBL9265159 | 0.89 | CA2 (0.43) | CA2CA4CA1CA12CA6 | |
| SCHEMBL9262093 | 0.88 | CA2 (0.51) | CA2CA4CA1CA12CA6 | |
| SCHEMBL9264301 | 0.80 | CA2 (0.46) | CA2CA4CA1CA12CA6 | |
| SCHEMBL9263901 | 0.79 | CA2 (0.52) | CA2CA4CA1CA12CA6 | |
| SCHEMBL9261563 | 0.77 | CA2 (0.50) | CA2CA4CA1CA12CA6 | |
| SCHEMBL9267013 | 0.77 | CA2 (0.51) | CA2CA4CA1CA12CA6 | |
| SCHEMBL8704983 | 0.77 | CA2 (0.59) | CA2CA4CA1CA12CA6 | |
| SCHEMBL8714833 | 0.77 | CA2 (0.59) | CA2CA4CA1CA12CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378703-A | FOR CONTROLLING INTRAOCULAR PRESSURE | ALCON LABORATORIES, INC. (US) | 1995-01-03 | — | — | US | claimed |