Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 12/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5164870 | 0.84 | FFAR4 (0.47) | FFAR4FFAR1KEAP1MEN1KMT2A | |
| SCHEMBL16177255 | 0.78 | CTSL (0.36) | FFAR4KMT2A | |
| SCHEMBL9316292 | 0.77 | FFAR4 (0.41) | FFAR4FFAR1KEAP1HTTSLC1A3 | |
| SCHEMBL9020639 | 0.75 | TSHR (0.40) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 | |
| SCHEMBL9316297 | 0.74 | SLC1A3 (0.36) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 | |
| SCHEMBL13512970 | 0.73 | HTT (0.51) | HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19094203 | 0.71 | TSHR (0.40) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 | |
| SCHEMBL19745328 | 0.71 | SLC1A3 (0.45) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 | |
| SCHEMBL21638945 | 0.71 | TSHR (0.43) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 | |
| SCHEMBL20551920 | 0.71 | TSHR (0.43) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641327-A1 | NOVEL ALPHA-MANNOSIDASE INHIBITORS | MERRELL PHARMACEUTICALS INC. (US) | 1995-03-08 | — | — | EP | disclosed |
| WO-1993005781-A1 | NOVEL ALPHA-MANNOSIDASE INHIBITORS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-04-01 | — | — | WO | disclosed |