Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9020639 | 0.92 | TSHR (0.40) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL31721379 | 0.87 | GRIN1 (0.36) | TSHRCYP2C19KMT2AOPRM1OPRD1 | |
| SCHEMBL20552640 | 0.83 | SLC1A3 (0.40) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL15130271 | 0.83 | TSHR (0.39) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL31114231 | 0.80 | TSHR (0.43) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL23275795 | 0.77 | CA2 (0.41) | TSHRSLC1A3SLC1A2SLC1A1CYP1A2 | |
| SCHEMBL12981785 | 0.74 | NR5A2 (0.41) | TSHROPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL19094203 | 0.73 | TSHR (0.40) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8566404 | 0.73 | TSHR (0.40) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL31114220 | 0.73 | ALDH1A1 (0.45) | SLC1A3SLC1A2SLC1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260137706-A1 | METHODS OF TREATING INFLAMMATORY DISEASES | INTERLINE THERAPEUTICS INC (US) | 2026-05-21 | — | — | US | disclosed |
| EP-4724440-A1 | METHODS OF TREATING INFLAMMATORY DISEASES | Interline Therapeutics, Inc. (US) | 2026-04-15 | — | — | EP | disclosed |
| US-12527763-B2 | Pyrrole amide compound and use thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2026-01-20 | — | — | US | disclosed |
| WO-2024254539-A1 | METHODS OF TREATING INFLAMMATORY DISEASES | INTERLINE THERAPEUTICS, INC. (US) | 2024-12-12 | — | — | WO | disclosed |
| CN-118684666-A | KIF18A inhibitors and uses thereof | 诺沃斯达药业(上海)有限公司 | 2024-09-24 | — | — | CN | disclosed |
| WO-2023083191-A1 | BENZODIAZEPINE COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 四川大学华西医院 | 2023-05-19 | — | — | WO | disclosed |
| US-20220211665-A1 | PYRROLE AMIDE COMPOUND AND USE THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2022-07-07 | — | — | US | disclosed |
| CN-114702427-A | Pyrrole amide compound and application thereof | 年衍药业(珠海)有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-112707854-B | Pyrrole amide compound and application thereof | 年衍药业(珠海)有限公司 | 2022-03-15 | — | — | CN | disclosed |
| EP-3950674-A1 | PYRROLE AMIDE COMPOUND AND USE THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2022-02-09 | — | — | EP | disclosed |
| US-11186554-B2 | Non-fused tricyclic compounds | VIVACE THERAPEUTICS, INC. (US) | 2021-11-30 | — | — | US | disclosed |
| US-11186554-B2 | Non-fused tricyclic compounds | VIVACE THERAPEUTICS, INC. (US) | 2021-11-30 | — | — | US | disclosed |
| WO-2021078135-A1 | PYRROLE AMIDE COMPOUND AND USE THEREOF | 广东东阳光药业有限公司 | 2021-04-29 | — | — | WO | disclosed |
| CN-112707854-A | Pyrrole amide compound and application thereof | 广东东阳光药业有限公司 | 2021-04-27 | — | — | CN | disclosed |
| CN-111132673-A | Non-fused tricyclic compounds | 维瓦斯治疗公司 | 2020-05-08 | — | — | CN | disclosed |
| EP-3618818-A1 | NON-FUSED TRICYCLIC COMPOUNDS | Vivace Therapeutics, Inc. (US) | 2020-03-11 | — | — | EP | disclosed |
| US-20200062721-A1 | NON-FUSED TRICYCLIC COMPOUNDS | VIVACE THERAPEUTICS, INC. | 2020-02-27 | — | — | US | disclosed |
| US-20200062721-A1 | NON-FUSED TRICYCLIC COMPOUNDS | VIVACE THERAPEUTICS, INC. | 2020-02-27 | — | — | US | disclosed |
| WO-2018204532-A1 | NON-FUSED TRICYCLIC COMPOUNDS | VIVACE THERAPEUTICS, INC. (US) | 2018-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062721-A1 | NON-FUSED TRICYCLIC COMPOUNDS | YAP1, MYC, TEAD2 | TSHR 2644/4885IDO1 3967/4885SLC1A3 4249/4885 |
| US-20260137706-A1 | METHODS OF TREATING INFLAMMATORY DISEASES | NR3C1, CCR1, CXCR2 | TSHR 1291/4885IDO1 599/4885SLC1A3 3048/4885 |
| US-12527763-B2 | Pyrrole amide compound and use thereof | NR3C2, AVPR2, MC2R | TSHR 86/4885IDO1 3323/4885SLC1A3 531/4885 |
| US-11186554-B2 | Non-fused tricyclic compounds | YAP1, MYC, TEAD2 | TSHR 2644/4885IDO1 3967/4885SLC1A3 4249/4885 |
| US-20220211665-A1 | PYRROLE AMIDE COMPOUND AND USE THEREOF | MC2R, NR3C2, AVPR2 | TSHR 97/4885IDO1 3889/4885SLC1A3 2219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.