Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | CDC25A | P30304 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | CDC25C | P30307 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9263382 | 0.72 | LOXL2 (0.40) | CYP11B1CYP11B2LOXL2CYP19A1HRH3 | |
| SCHEMBL2354871 | 0.72 | CYP11B2 (0.48) | CYP11B1CYP11B2LOXL2CYP19A1HRH3 | |
| SCHEMBL14155434 | 0.71 | LOXL2 (0.58) | CYP11B2LOXL2CYP19A1HRH3CYP2A6 | |
| SCHEMBL16848648 | 0.71 | LOXL2 (0.58) | CYP11B2LOXL2CYP19A1HRH3CYP2A6 | |
| Hydrochloric Acid SCHEMBL1507784 | 0.71 | CYP11B2 (0.47) | CYP11B1CYP11B2LOXL2CYP19A1HRH3 | |
| SCHEMBL9790872 | 0.69 | CYP11B2 (0.48) | CYP11B1CYP11B2CYP19A1HRH3LRRK2 | |
| SCHEMBL1344068 | 0.69 | LOXL2 (0.65) | LOXL2CYP19A1HRH3CYP2A6SAE1 | |
| SCHEMBL9165264 | 0.67 | CYP11B2 (0.43) | CYP11B1CYP11B2CYP19A1NSD2GAA | |
| SCHEMBL2352121 | 0.66 | CYP11B1 (0.45) | CYP11B1CYP11B2LOXL2CYP19A1HRH3 | |
| SCHEMBL2356830 | 0.64 | CYP11B1 (0.43) | CYP11B1CYP11B2LOXL2CYP19A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378721-A | AROMATASE INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1995-01-03 | — | — | US | disclosed |
| US-5246952-A | Antitumor agents | CIBA-GEIGY CORPORATION (US) | 1993-09-21 | — | — | US | disclosed |