Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3582119 | 0.71 | HIPK2 (0.36) | HIPK2ALDH1A1SMN1; SMN2 | |
| SCHEMBL29220900 | 0.67 | NOTUM (0.39) | HIPK2ALDH1A1 | |
| SCHEMBL2068718 | 0.65 | HIPK2 (0.35) | HIPK2ALDH1A1SMN1; SMN2 | |
| SCHEMBL308284 | 0.64 | F2RL1 (0.41) | HIPK2ALDH1A1SMN1; SMN2 | |
| SCHEMBL10919818 | 0.63 | CYP2A6 (0.39) | HIPK2ALDH1A1SMN1; SMN2 | |
| SCHEMBL114028 | 0.61 | HIPK2 (0.41) | HIPK2ALDH1A1SMN1; SMN2 | |
| SCHEMBL3527181 | 0.60 | HIPK2 (0.37) | HIPK2ALDH1A1SMN1; SMN2 | |
| SCHEMBL753318 | 0.59 | HIPK2 (0.36) | HIPK2ALDH1A1SMN1; SMN2 | |
| SCHEMBL300491 | 0.58 | ALOX15 (0.41) | HIPK2ALDH1A1SMN1; SMN2 | |
| SCHEMBL1899917 | 0.58 | DRD4 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5411982-A | Cycloalkylene azoles, and their use as aromatase inhibitors | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-05-02 | — | — | US | disclosed |